525@vine – Office Space for Lease Winston Salem

Aerial view of 525@vine

Space for Rent in 525@vine

This 234,000 square foot five-story mixed-use building sits in the heart of the Innovation Quarter. Adjacent to Bailey Park and connected to the Long Branch Trail, 525@vine is an ideal location for any company looking to find their spot in the Innovation Quarter.

525@vine houses several Wake Forest School of Medicine programs, local businesses and community amenities. A former RJR tobacco factory building, 525@vine now features a mix of lab and office space, as well as a soaring atrium. A large surface parking lot adjacent to the building is available for tenants and their visitors.


525 Vine Street
Winston-Salem, NC 27101

Available Office Space

525@vine has a 10,060 square foot full-service office space available. This space features a lobby/reception area, two additional rooms, and a large open area with high ceilings and bathrooms with showers. This space can be fitted with private offices, open workstations and conference rooms.

Be In Good Company

Innovation Quarter Amenities

115+ Restaurants within a Mile

Exclusive Events for Tenants

Parking for Tenants and Visitors

24-hour Security