Wake Forest Innovation Quarter in downtown Winston-Salem, North Carolina, offers a unique urban home to millions of square feet in office, laboratories and educational spaces. It supports biomedical science, technology and information technology companies, and nationally recognized universities destined to change the world through innovation, collaboration and creativity.


With 234,000 square footage, the five-story building features a mixed use of lab and office space for tenants, such as the Innovation Quarter YMCA, Mullenlowe and Flywheel Coworking, and a large open atrium.

Albert Hall

Located at 101 N. Chestnut Street, Albert Hall offers four stories and 89,240 square feet of flexible professional space with tailored floor plans and houses a diverse portfolio of tenants composed of corporate, government and non-profit businesses.

Bailey Power Plant North

The former R.J. Reynolds Tobacco Company’s coal-fired power plant is now the five-story Bailey Power Plant North and located at 486 N. Patterson Avenue. The 110,800-square-foot building houses companies and restaurants, such as Wake Forest Innovations, Fluree and Alma Mexicana, and offers office, entertainment and retail space.

Bowman Gray Center for Medical Education

Located at 475 Vine Street, the six-story building boasts 168,000 square feet of responsive, cutting-edge facilities, including tiered classrooms, clinical skills labs and patient simulation suites, for biomedical research and education.

Center for Design Innovation

Located at 450 Design Avenue, near Rams Drive, the Center for Design Innovation, a three-story building with 27,000 square feet, is a multi-campus research center that focuses on collaborative design research and includes Winston-Salem State University, UNC School of the Arts and Forsyth Technical Community College.

Downtown Health Plaza

Located at 1200 N. Martin Luther King Jr. Drive, the Downtown Health Plaza is a two-story outpatient clinic with 47,348 square feet dedicated to providing diagnostic and treatment services, prescription assistance, and more.

Inmar Headquarters

Located at 635 Vine Street, Inmar’s three-story, LEED platinum-certified building is headquartered in Winston-Salem with 240,000 square feet of tobacco warehouse redesigned to accommodate technology-centered product and service offerings.

Krankies Block

Located at 211 East 3rd Street, this three-story building with 15,268 square feet, is a small batch roaster and café offering a diverse menu of food for breakfast, lunch and dinner with a full bar.

Piedmont Triad Community Research Center (PTCRC)

Located at 115 S. Chestnut Street, the Piedmont Triad Community Research Center (PTCRC) has three stories and 100,185 square feet of laboratories and animal research facilities. Owned by Wake Forest University Health Sciences, the building became the first in what is now the Wake Forest Innovation Quarter.

One Technology Place

Located at 200 E. First Street, One Technology Place, a four-story building with 108,900 square feet, is managed by Wake Forest University and offers 82 available office spaces for lease. The building houses a variety of companies, including Kucera Pharmaceutical Company, Pleasants Properties and Cain Hahn Associates.

Richard H. Dean Biomedical Research Building

Located at 391 Technology Way, the Richard H. Dean Biomedical Research Building, a four-story building with 180,434 square feet, is a mutli-tenant, advanced research facility that houses Wake Forest Institute for Regenerative Medicine and includes an adjacent parking deck.

S.J. Nissen Building

Located on 310 E. Third Street, the S.J. Nissen Building, a three-story building with a two-story basement and 21,780 square feet, features two crenellated front towers and houses companies, such as Kester Machinery Company and Black Horse Studio.

Victoria Hall

Located at 111 Chestnut Street, Victoria Hall is a three-story, downtown Class A building with historic designations and 45,000 square feet. Victoria Hall features flexible floor plans for professional businesses and includes on-site management and parking.

Wake Forest Biotech Place

Located at 575 Patterson Avenue, the five-story building boasts 242,000 square feet of the latest technological bells and whistles needed to advance modern science and innovation, including custom-built laboratories, conference rooms and a large atrium for events.

Wake Downtown

Located at 455 Vine Street, Wake Downtown, a five-story building with 115,000 square feet, is the locus of Wake Forest University’s three new undergraduate academic programs in biochemistry and molecular biology, medicinal chemistry and drug discovery, and engineering and includes classrooms, teaching labs and research labs for students.

Wells Fargo Linden Center

Located at 401 N. Research Parkway, Wells Fargo Linden Center is a three-story, Class A office building and features a total of 193,510 square feet with 77 office spaces for lease.

Coming Soon: Bailey Power Plant South

Coming to the corner of E. 4th Street and Patterson Avenue, the 75,000-square-foot building Bailey Power Plant South will have six floors and house local marketing agency The Variable along with new restaurants and retail space.

For more information about leasing space at buildings in Innovation Quarter, please call Will Partin at +1.336.713.1336 or email him at